Sorry for not addressing so much of your comment No probs. You don't have to.
I do not believe a muscle cell can utilize lactate directly for energy and it is just a waste product to a muscle cell.
Well you definitely should. Because before blood lactate gets recycled in glucose then glycogen through the Cori Cycle, your system will try to use it as a fuel directly:
Clearance of lactate from the blood can occur either through oxidation within the muscle fibre in which it was produced or it can be transported to other muscles fibres for oxidation (31,30). Lactate that is not oxidized in this way diffuses from the exercising muscle into the capillaries and it is transported via the blood to the liver (31). Through a process known as the Cori cycle, lactate can be converted to pyruvate in the presence of oxygen, which can then be converted into glucose (2). This glucose can either be metabolized by working muscles or stored in the muscles as glycogen for later use (2). www.sport-fitness-advisor.com/lactic-acid.html
To the best of my knowledge, the process during which blood lactate is brought some place else where it can be oxidized is called Lactate Shuffle. And the process in which lactic acid is used as a fuel would be called Lactate metabolism. Because it is really what it is. Lactate is being used as a fuel here, inside muscle cells. Again here, fairly high level. Lactic Acid (which is the name we should give to lactate before it enters in your blood stream) gets converted back to Pyruvate. Can then enter mitochondria so that it can get oxidized by o2.
Some physiologists believe that without this process, it would be impossible to sustain high threshold velocities for prolonged durations. A lot believe that the glycogen pool availability can not, in itself, justify how you can remain at maxlass for 45 straight minutes. Lactate is a powerful fuel. And not only this, physiologists also believe that in a lot of areas, your body prefers to deal with lactate compared to with sugar for instance. The heart itself loves this as much as an alcoholic may appreciate beer. The heart, brain and most slow twitch fibers are very apt at clearing lactate from the blood to the extent that they prefer lactate as a source of fuel (27,28,29). Note however, that lactate must first be converted into pyruvate before it can be used as a source of energy.
Sorry for not addressing so much of your comment No probs. You don't have to.
I do not believe a muscle cell can utilize lactate directly for energy and it is just a waste product to a muscle cell.
Well you definitely should. Because before blood lactate gets recycled in glucose then glycogen through the Cori Cycle, your system will try to use it as a fuel directly:
Clearance of lactate from the blood can occur either through oxidation within the muscle fibre in which it was produced or it can be transported to other muscles fibres for oxidation (31,30). Lactate that is not oxidized in this way diffuses from the exercising muscle into the capillaries and it is transported via the blood to the liver (31). Through a process known as the Cori cycle, lactate can be converted to pyruvate in the presence of oxygen, which can then be converted into glucose (2). This glucose can either be metabolized by working muscles or stored in the muscles as glycogen for later use (2). www.sport-fitness-advisor.com/lactic-acid.html
To the best of my knowledge, the process during which blood lactate is brought some place else where it can be oxidized is called Lactate Shuffle. And the process in which lactic acid is used as a fuel would be called Lactate metabolism. Because it is really what it is. Lactate is being used as a fuel here, inside muscle cells. Again here, fairly high level. Lactic Acid (which is the name we should give to lactate before it enters in your blood stream) gets converted back to Pyruvate. Can then enter mitochondria so that it can get oxidized by o2.
Some physiologists believe that without this process, it would be impossible to sustain high threshold velocities for prolonged durations. A lot believe that the glycogen pool availability can not, in itself, justify how you can remain at maxlass for 45 straight minutes. Lactate is a powerful fuel. And not only this, physiologists also believe that in a lot of areas, your body prefers to deal with lactate compared to with sugar for instance. The heart itself loves this as much as an alcoholic may appreciate beer. The heart, brain and most slow twitch fibers are very apt at clearing lactate from the blood to the extent that they prefer lactate as a source of fuel (27,28,29). Note however, that lactate must first be converted into pyruvate before it can be used as a source of energy.
